Ocular Oncology Course

Sunday, October 15th, 2017 | 8AM-Noon | Grand Ballroom 5, 3rd floor level

Inspired by Dr. Carol Shields’ Keynote Lecture, “The Colorful Spectrum of Ocular Tumors in Humans,” the Sunday course will focus on Ocular Oncology. The goal of this course is to provide the attendee with an update on recent developments in the better understanding and diagnosis of ocular neoplasms in and around the eyes of animals. Time has been scheduled for interactive discussion with the speakers. Registration fee includes a 4-hour CE certificate, breakfast before the course, and coffee break refreshments.


7:00am-8:00am     Breakfast & Welcome

8:00am-8:40am     Dr: Richard R. Dubielzig: "Epidemiology of Ocular Neoplasia in Domestic Animals"

8:40am-9:20am     Dr. Dodd Sledge: "So Now What? Immunohistochemistry in Ocular Pathology"     

9:20am-10:00am   Dr. Leandro Teixeira:  "What’s New in Ocular Neoplasia?"                                    

10:00am-10:30am  Coffee Break & Discussion

10:30am-11:10am   Dr. Mary Lassaline: "Genetics of Ocular Squamous Cell Carcinoma in Horses"

11:10am-11:45am    Dr. Amy Durham: "Clinical and Pathological Characterization of Intraocular Lymphoma in Dogs and Cats"

11:45am-Noon:  Q&A                                 

Speakers & Topics

Richard R. Dubielzig, DVM, DACVP, Hon.DACVO

"Epidemiology of Ocular Neoplasia in Domestic Animals"

We know little about the risk factors associated with the occurrence of tumors in and around the eyes of animals. Dr. Dubielzig will mine the COPLOW database to uncover some interesting trends regarding the demographics and other factors which impact the development of neoplasms. Clinicians will better understand the kinds of animals at risk of various tumors and they will be better informed about the potential risks of therapy in oncogenesis.

About Dr. Dubielzig

Richard Dubielzig graduated from Veterinary School in the class of 1972 at the University of Minnesota.  After two years of small animal practice in New York state he began a pathology residency at the University of Pennsylvania in 1974 leading to board certification in 1977.  Dr Dubielzig stayed at the University of Pennsylvania as a faculty member in anatomic pathology. During his residency, he first became interested in ocular pathology and he was mentored in ophthalmology by Gustavo Aquirre.  In 1983 Dr Dubielzig returned to his home town of Madison Wisconsin where he was the charter faculty member of the new Pathobiological Sciences where he remains as Professor of Pathology.  He is the founding director of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW).  In 2004 Dr Dubielzig was made an honorary diplomate of the ACVO.  In July of 2014 he retired from the university but continues to be productive as a volunteer in the COPLOW.  COPLOW is a large mail-in ocular pathology service. 

Dr. Dubielzig has authored more than 300 original articles mostly describing the morphologic changes in the spontaneous diseases of the eye in animals.  The archived collection of the Comparative Ocular Pathology Lab of Wisconsin (COPLOW) exceeds 56,000 accessions and is available as a teaching or research resource. 

Dodd Sledge, DVM, PhD, DACVP

Diagnostic Center for Population and Animal Health (DCPAH)

Michigan State University, East Lansing

"So Now What? Immunohistochemistry in Ocular Pathology"

Dr. Sledge will briefly cover immunohistochemical techniques and commonly used immunohistochemical markers in ocular pathology, with an emphasis on diagnosis and prognostication of ocular neoplasms.

About Dr. Sledge

Dr. Dodd Sledge, DVM, PhD, DACVP is an academic specialist in anatomic pathology at the Michigan State University Veterinary Diagnostic Laboratory. He specializes in ocular pathology in both research and diagnostics, and has particular interests in diagnosis and prognostication of ocular tumors using a wide array of molecular diagnostic tools, such as immunohistochemistry.

Leandro Teixeira, DVM, MS, DACVP

The Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) - University of Wisconsin-Madison

"What’s New in Ocular Neoplasia?"

The lecture will contain a discussion of the most recent developments in ocular oncology in dogs and cats with emphasis in the clinicopathological aspects of selected ocular tumor in dog and cats and implications for diagnostic, prognosis and treatment.


Amy C. Durham, MS, VMD, DACVP

Department of Pathobiology

University of Pennsylvania, Philadelphia

"Clinical and Pathological Characterization of Intraocular Lymphoma in Dogs and Cats"

Dogs and cats with intraocular lymphoma may present without any signs of systemic involvement at the time of enucleation; these cases are referred to as presumed solitary ocular lymphoma (PSOL). The true proportion of patients with PSOL versus secondary ocular involvement and the prognostic implications of intraocular lymphoma are not well understood.   This presentation describes retrospective studies that investigated dogs and cats with ocular lymphoma to better characterize and correlate clinical signs, histomorphologic and immunohistochemical features, WHO classification of the subtypes of ocular lymphoma, clinical progression of disease, and overall patient outcome.

Mary Lassaline, DVM, PhD, MA, DACVO

University of California-Davis

"Genetics of Ocular Squamous Cell Carcinoma in Horses"

Squamous cell carcinoma (SCC) is the most commonly diagnosed ocular cancer in horses, and can be associated with loss of vision, loss of the globe, and in cases with aggressive local or metatstatic spread, loss of life.  The etiopathogenesis of ocular SCC is not entirely understood but several factors are thought to be involved, including UV radiation, viral exposure and hormonal regulation.  Breed predispositions for ocular SCC suggest genetics as a significant contributor to ocular SCC.  A mutation in a DNA-repair gene has been associated with increased risk of ocular SCC in at least two horse breeds.  Recent research on the genetics of ocular SCC including a review of the methodology involved in identifying the mutation will be presented.

About Dr. Lassaline

Mary Lassaline, DVM, PhD, Department of Radiological and Surgical Sciences, School of Veterinary Medicine, is an Associate Professor of Clinical Equine Ophthalmology at the University of California-Davis. Dr. Lassaline earned a PhD in cognitive psychology at the University of Michigan, attended veterinary school at Michigan State University and completed an internship in equine medicine and surgery at Rood and Riddle Equine Hospital in Lexington, Kentucky followed by a veterinary ophthalmology residency at the University of Florida.  She is a Diplomate of the American College of Veterinary Ophthalmologists.  She has a special interest in equine corneal disease.